Treating Anemia in the Newborn

Your newborn has been diagnosed with anemia. This means the baby’s blood contains fewer red blood cells than normal. Red blood cells carry oxygen throughout the body. When a baby has anemia, the body doesn’t get enough oxygen. As a result, the baby feels tired and has less energy. Many babies have mild anemia within a few months after birth. These cases don’t require treatment. But your baby’s anemia is more severe. It must be treated to bring the red blood cell count back up. A blood test called a complete blood count (CBC) can tell us if your child has anemia.  This test is often part of regular tests your baby has  in the hospital.

Signs of possible anemia in a newborn

• Short periods of not breathing (apnea)
• Fast breathing
• Pale skin
• Poor weight gain
• Decreased activity
• Fast heart rate (tachycardia)
• Severe swelling (hydrops) 

Causes of anemia

Your baby’s anemia is likely caused by at least one of these problems:

• Blood loss. This is a common cause of anemia in babies in the NICU (neonatal intensive care unit). This is because blood must be taken from the baby so certain tests can be done. Because of this risk, NICUs try to limit the amount of blood drawn as much as possible. A baby who has a hemorrhage (internal bleeding) could also become anemic. In some cases, some of the baby’s blood moves into the mother’s bloodstream during pregnancy. As a result, the baby has less blood. This is called a fetal-maternal transfusion. Blood loss can also occur in twins if one twin got less blood than the other during pregnancy (called a twin-to-twin transfusion).
• Low red blood cell production. This occurs if the baby doesn’t get enough iron (a nutrient that helps build red blood cells). Normally, the baby’s body stores iron during the last months of pregnancy. When a baby is born early, less iron is stored and the body is less able to respond to the need to make more red blood cells.
• Shortened red blood cell life (hemolysis). This means the baby’s red blood cells aren’t living as long as they’re supposed to. Newborn red blood cells don't live as long as adults' red blood cells do. Also in some newborns, the baby’s blood type is incompatible with the mother’s blood type. During pregnancy, the mother’s body made substances called antibodies that fought against the baby’s red blood cells. These antibodies are now in the baby’s blood. As a result, the baby’s red blood cells don’t live as long. Hemolysis can have other causes, too. Talk with the healthcare provider about the cause of your baby’s hemolysis.

Treatments for anemia

• A blood transfusion puts healthy donor blood into the baby’s body. This is done through an IV (intravenous) line. The donor blood helps bring the baby’s red blood cell count back to normal.  Your baby may need more than one blood transfusion during the hospital stay.
• Medicine may be given to the baby through an IV line or by injection. The medicine prompts the baby’s body to make more red blood cells. This treatment is not routinely used and may have side effects.

What are the long-term effects?

Once treated, anemia does not cause long-term complications for most babies. Talk with the healthcare provider about how your baby is likely to progress.

© The StayWell Company, LLC. 800 Township Line Road, Yardley, PA 19067. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions. This information has been modified by your health care provider with permission from the publisher.